Errors made by 'DNA spellchecker' revealed as important cause of cancer

Important processes that create mutations that cause cancer have been identified by researchers studying the genomes of more than 1,000 tumors. Many mutations in human cancers are caused by mistakes made by a repair mechanism or ‘DNA spellchecker’ rather than the actual damage to DNA caused by the environment. Sunlight and alcohol consumption increase the […]

Lab-created mini-brains reveal how growing organ maintains neuronal balance

Scientists can now explore in a laboratory dish how the human brain develops by creating organoids — distinct, three-dimensional regions of the brain. Scientists coaxed early stage stem cells to create and fuse two types of organoids from different brain regions to show how the developing brain maintains proper balance of excitatory and inhibitory neurons. […]

Sticky when wet: Strong adhesive for wound healing

A super-strong ‘tough adhesive’ has been created that is non-toxic and binds to biological tissues with a strength comparable to the body’s own resilient cartilage, even when they’re wet. Inspired by the glue produced by a slug, the double-layered hydrogel material demonstrates both high adhesion strength and strain dissipation, making it useful in a variety […]